Alzheimer’s disease (AD, commonly known as “senile dementia”) is a common, irreversible senile disease of unknown origin, usually caused by chronic progressive degeneration of the central nervous system.
Clinical manifestations are memory impairment, aphasia, apraxia, agnosia, visual-spatial distance impairment, executive dysfunction, and personality and behavioral changes. As the disease progresses, patients gradually lose their ability to take care of themselves.
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that is widely used by clinicians and neuroscientists to treat psychiatric and neurological disorders.
Studies have found that tDCS can improve cognitive function and psychobehavioral symptoms of AD by modulating neuroplasticity, brain networks, neurotransmitters, and nutritional factors.
tDCS usually takes 10 sessions as a course of treatment. In order to compare the efficacy of short-term tDCS and long-term tDCS in patients with Alzheimer’s disease, foreign scholars conducted randomized controlled studies to explore the clinical efficacy of the two.
Extensive laboratory data suggest that both short- and long-term interventions with anodal tDCS have a role in slowing specific neurophysiological activity in AD patients. In both short- and long-term interventions, the experimental group maintained the same level of neuropsychological performance as before the intervention, while participants in the sham group showed a significant decline. In addition, long-term tDCS can have an effect on EEG patterns in AD patients. In conclusion, short- and long-term anodal tDCS stimulation of the left frontotemporal lobe is an effective approach to slow Alzheimer’s progression.
ELITEMED series Transcranial direct current stimulator (tDCS) use a non-invasive technology that uses constant,low-intensity current (0-2mA) to modulate nerves. The amount of intracranial current affects the activation of neuronal cells, the excitability depends on the level of the electrodes, and the degree of excitation also affects the changes in brain function.
The number of Alzheimer’s patients in my country has reached tens of millions, and with the intensification of the aging population, the number of such patients is bound to increase significantly. it means this market is full of potential.